Custom Prescription Skincare with Tretinoin, Niacinamide & Hyaluronic Acid | Clear, Smooth, Youthful Skin Provided by ARSYNL Rx

Name: Skincare
Brand: Arsynl
Price: 89.00 USD
Availability: InStock

At ARSYNL Rx, we combine Tretinoin, Niacinamide, and Hyaluronic Acid into one custom prescription skincare formula designed to promote clearer, smoother, and more youthful-looking skin. Tretinoin supports cell turnover and acne management, Niacinamide helps reduce redness and improve skin tone, while Hyaluronic Acid deeply hydrates for a balanced complexion. Each treatment plan is reviewed by U.S.-licensed providers through our secure telehealth platform to ensure safety and personalized strength. Results and response times vary by individual. Experience dermatologist-backed skincare with ARSYNL Rx’s prescription Tretinoin blend—where advanced science meets radiant, healthy skin.

Fast free delivery

U.S. board certified physicians

Trusted medications, money back guarantee

$89.00 USD

What Is Tretinoin, Niacinamide & Hyaluronic Acid Skincare and How Does It Work?

ARSYNL Rx’s custom skincare formula blends three dermatologist-backed, clinically proven ingredients — Tretinoin, Niacinamide, and Hyaluronic Acid — to deliver comprehensive anti-aging, acne-fighting, and skin-restoring results.

Each ingredient plays a unique role in improving skin health and appearance:

Tretinoin (Vitamin A derivative): A potent retinoid that accelerates cellular turnover, unclogs pores, and stimulates collagen production for smoother, firmer, and more radiant skin.
Niacinamide (Vitamin B3): Helps strengthen the skin barrier, minimize redness and inflammation, balance oil production, and reduce hyperpigmentation.
Hyaluronic Acid: A deeply hydrating molecule that attracts and retains moisture, plumping the skin to reduce the appearance of fine lines and dryness.

Together, these powerhouse ingredients work synergistically to renew the skin at multiple levels — resurfacing texture, restoring balance, and reinforcing long-term hydration and protection. This multi-active formula supports both preventive and corrective skincare for all skin types.

Skincare tools including a jade roller and face mask on a towel with a candle in the background.

Man applying skincare in a bathroom with plants and candles in the background

What Are the Benefits of Tretinoin, Niacinamide & Hyaluronic Acid Skincare?

This advanced skincare combination provides both immediate and long-term benefits for a visibly healthier complexion. It targets core concerns like aging, acne, dullness, and dehydration, making it one of the most comprehensive topical treatments available through medical-grade formulations.

Key benefits may include:

Improved skin texture and tone through increased cell renewal
Reduction in fine lines, wrinkles, and age spots
Balanced oil production and reduced breakouts
Enhanced hydration and elasticity for a plumper appearance
Strengthened skin barrier and improved resilience to environmental stress
Brighter, more even complexion with continued use

By combining exfoliating, brightening, and hydrating effects in one treatment, this formula helps reveal healthier, smoother, and more youthful-looking skin — a cornerstone of ARSYNL Rx’s performance-driven skincare approach.

How it works

Step - 1

Take the health questionnaire

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100% online and confidential health intake form

Step - 2

Get your prescription

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All prescriptions overseen by fully licensed and insured physicians

Step - 3

Get your meds

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Fast free delivery from our accredited pharmacies

Why choose ARSYNL Rx Telemedicine?

US-licensed professionals

Experienced healthcare providers committed to your well-being.

No insurance needed

Upfront pricing, with no hidden fees.

Ongoing medical support

Ongoing assistance with your specific health condition

Frequently Asked Questions

Tretinoin is a prescription cream that belongs to a class of medications called retinoids. Tretinoin minimizes the appearance of fine lines and wrinkles by increasing the production of collagen which is a protein that provides a powerful support network for your skin. Collagen production drops by about 1% every year after you enter your 20’s and this contributes to aging skin. Tretinoin also stimulates the production of new blood vessels in the skin, which improves skin color. Additional benefits include fading age spots and softening rough patches of skin. The VIP of skin care products!

Niacinamide is a form of vitamin B3. It reduces inflammation and helps with the production of ceramides (which are like the bricks that build your skin barrier). Additionally, it improves the smoothness of your skin and reduces dark spots.It’s a true skincare multitasker!

Hyaluronic acid is a naturally occurring substance in your body that’s great at retaining moisture. Think of it as a hydration superhero for your skin. When used in skincare products, it helps keep your skin plump, hydrated, and youthful by attracting and holding onto water molecules. A must for skin care!

Hydroquinone is a skin-lightening agent that helps with dark spots and hyperpigmentation. This compound works by inhibiting the production of melanin, the pigment responsible for skin color. In simpler terms, it can help lighten those pesky dark spots, sunspots, age spots, or acne scars. Works wonders!

Hydrocortisone is a topical, mild steroid that helps reduce inflammation, swelling, redness and itching. An added boost if needed!

Tretinoin has a few precautions that you should be aware of. A brief sensation of warmth or stinging may occur immediately after applying the medication. Skin redness, dryness, itching, scaling or mild burning may occur during the first 2-4 weeks of using the medication. These effects usually decrease with continued use.

Topical Niacinamide is generally well-tolerated but may cause mild burning, itching, or redness.

Hyaluronic acid is generally well-tolerated since it is already produced in the body. Rarely, a topical allergic reaction may occur.

Common side effects of Hydroquinone include redness, dryness, and irritation. Hydroquinone has the risk of producing a condition called exogenous ochronosis which is a gradual blue-black darkening of the skin. This risk is more common in darker skin types, with use of Hydroquinone strengths greater than 4% and when treatment is prolonged beyond 3 months without breaks in therapy; however, this adverse effect can also develop at any time during treatment with Hydroquinone. The occurrence of any signs of blue-black darkening of the skin should prompt immediate discontinuation of therapy with Hydroquinone. Studies of Hydroquinone in animals have demonstrated some evidence of carcinogenicity, but the carcinogenic potential of Hydroquinone in humans is unknown.