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Premature Ejaculation

Premature Ejaculation Treatment Online | Sertraline Prescription for Improved Control Provided by ARSYNL Rx

At ARSYNL Rx, we offer Sertraline prescription therapy for men seeking support with premature ejaculation under the care of U.S.-licensed providers. Sertraline, a selective serotonin reuptake inhibitor (SSRI), may help improve ejaculatory control and sexual confidence when prescribed appropriately. Our secure telehealth platform allows for discreet evaluation, personalized treatment planning, and direct-to-door delivery for convenience and privacy. Each plan is individually reviewed to ensure safety, proper dosing, and effectiveness. Results vary based on individual response. Take control of your sexual wellness with ARSYNL Rx’s prescription Sertraline treatment for premature ejaculation—where clinical expertise meets confidential care.

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$90.00 USD

What Is Sertraline and What to Expect When Using It for Premature Ejaculation?

Sertraline is a prescription medication classified as a selective serotonin reuptake inhibitor (SSRI), traditionally used to treat mood and anxiety disorders. However, it’s also been shown to effectively help manage premature ejaculation (PE) by increasing serotonin activity in the brain—one of the key neurotransmitters that influences sexual response and timing.

By gently adjusting serotonin levels, sertraline helps delay ejaculation, giving men more control, confidence, and satisfaction during sexual activity. It’s one of the most researched and clinically supported options for PE, often recommended when behavioral strategies or topical solutions are not sufficient on their own.

When starting sertraline for premature ejaculation, users may experience a gradual improvement over several weeks as the medication reaches steady levels in the body. Typical expectations include:


  • Improved ejaculatory control and longer duration before climax

  • Reduced performance anxiety and increased confidence

  • Enhanced sexual satisfaction for both partners

  • Stable mood and reduced stress related to sexual performance

Sertraline is generally well-tolerated when taken as prescribed. Some individuals may notice mild, temporary effects such as changes in sleep or appetite as their body adjusts. Over time, consistent use can support improved sexual function, greater control, and a restored sense of balance and confidence in intimate relationships.

How it works
Step - 1

Take the health questionnaire

100% online and confidential health intake form

Step - 2

Get your prescription

All prescriptions overseen by fully licensed and insured physicians

Step - 3

Get your meds

Fast free delivery from our accredited pharmacies

Why choose ARSYNL Rx Telemedicine?

US-licensed professionals

Experienced healthcare providers committed to your well-being.


No insurance needed

Upfront pricing, with no hidden fees.

Ongoing medical support

Ongoing assistance with your specific health condition

Frequently Asked Questions

What is Sertraline?

Sertraline is an oral tablet, prescription medicine that is widely used to treat Premature Ejaculation (PE).

How does Sertraline work?

Sertraline belongs to a group of drugs called selective serotonin reuptake inhibitors (SSRIs). Traditionally prescribed as an antidepressant, Sertraline is also very effective in helping men with Premature Ejaculation (PE) when taken daily in a low dose.

What can I expect with Sertraline treatment?

Taking Sertraline daily can greatly reduce PE. Researchers found that a 25mg daily dose of Sertraline lengthened the average ejaculatory interval (the time between the start of intercourse and ejaculation) from 1 minute to 7 minutes (600% increase!). You don’t have to time your dose or be bothered with topical applications, just take 1 tablet daily and PE is greatly reduced for most men.

How to take Sertraline?

Taking 1 tablet daily helps most men reduce their PE issue. It may take a few weeks for the medication to reach its full effect, so be patient and continue following your doctor’s instructions. Sertraline needs to be taken daily. If you skip days or doses, you may not receive the full benefit for PE.

What are the possible side effects of Sertraline?

Sertraline is often very well tolerated, especially at the low dose used for PE.  However, side effects may occur.  Some of the side effects are as follows:

  • Nausea: Feeling sick or queasy, which may occur initially but often improves with continued use.
  • Headache: Some people may experience mild to moderate headaches.
  • Insomnia or drowsiness: Sertraline can affect sleep patterns, leading to either difficulty sleeping (insomnia) or increased drowsiness.
  • Diarrhea or constipation: Changes in bowel movements may occur in some individuals.
  • Dry mouth: A common side effect that can cause discomfort.
  • Dizziness: Feeling lightheaded or dizzy.
  • Agitation or restlessness: In some cases, Sertraline may lead to increased feelings of anxiety or restlessness.
  • Suicidal thoughts: Although rare, some individuals may experience an increase in suicidal thoughts, especially when first starting the medication. Close monitoring is essential, especially in younger individuals.
What should I do if I miss a dose of Sertraline?

If you forget to take your daily dose of Sertraline, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should I store Sertraline?

Keep this medication in the original container that you received it in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

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