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What Is PT-141 and How Does It Work?
PT-141 (Bremelanotide) is a synthetic peptide therapy developed to support sexual arousal and performance in both men and women. Unlike traditional medications that target blood flow, PT-141 works through the central nervous system, stimulating areas of the brain involved in sexual desire and motivation.
This mechanism makes PT-141 unique—it helps address both psychological and physiological factors contributing to low libido or sexual dysfunction. Administered as a subcutaneous injection, it begins working within hours and can promote a natural, responsive sense of desire and readiness.
PT-141 acts on melanocortin receptors, key regulators of sexual behavior and arousal pathways, without relying on vascular mechanisms. This allows it to benefit individuals who may not respond fully to PDE-5 inhibitors such as sildenafil or tadalafil.
