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Home » Longevity » Low Dose Naltrexone

Longevity · Immune Modulation

Low Dose Naltrexone (LDN), Compounded and Prescribed Online

Low dose naltrexone prescribed and monitored by U.S.-licensed providers — a fraction of the standard dose, taken nightly, with four strengths so your provider can titrate carefully.

$75 / month

3-Month Plan
Save $12
$225 billed once
MOST POPULAR

Prescription products require an online consultation with a licensed provider who will determine whether a prescription is appropriate. Eligibility depends on health history, individual evaluation and clinical appropriateness. Compounded medications are not FDA-approved and are not evaluated by the FDA for safety or efficacy. Individual results vary. Not appropriate for everyone.

LegitScript Certified

HIPAA Compliant

US-Licensed Providers

Veteran-Founded & Operated

What patients describe

Where LDN Fits

LDN is prescribed off-label for a range of indications and is always a clinical decision. Patients who ask about it typically describe some combination of the following.

The medication

What Is Low Dose Naltrexone?

Naltrexone is an opioid receptor antagonist approved at 50 mg for alcohol and opioid dependence. At doses between roughly 1 and 4.5 mg — a small fraction of that — it is prescribed off-label for its proposed effects on immune signalling and microglial activity.

It is taken as a nightly oral capsule. Providers typically start low and titrate upward, which is why four strengths exist. Whether LDN is appropriate for you is a clinical decision based on your diagnosis, medications and history.

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Why ARSYNL Rx

Careful Titration, Not a Blanket Dose

LDN response is highly individual and starting too high is a common reason patients abandon it. ARSYNL Rx stocks four strengths so a provider can begin low and move upward at a pace you tolerate.

Every plan is reviewed by a U.S.-licensed provider, dispensed by a licensed pharmacy partner and followed with ongoing check-ins. Pricing is flat and the medication is included — there is no separate membership fee.

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In their words

A Word From Some ARSYNL Heroes

Real patients on low dose naltrexone therapy, in their own words, lightly edited for length.

How to use it

One Capsule, Taken at Night

Nightly at your provider-determined strength.

2

Start at the strength you were prescribed

Titration is deliberate. Do not move up on your own.

3

Note how you sleep in the first weeks

Vivid dreams and disrupted sleep are commonly reported early and often settle.

4

Report back before any change

Strength increases are clinical decisions based on your response.

The process

Physician-Guided From Intake to Delivery

Complete a Secure Online Intake

Health history, current medications, symptoms and your goals. Encrypted and HIPAA protected from the first question.

Review by a Licensed Provider

Licensed providers review your intake, symptoms and health history to determine whether therapy is appropriate for you.

Discreet Delivery & Ongoing Monitoring

If prescribed, medication is prepared by a licensed pharmacy partner and shipped to your door, with follow-up and provider check-ins over time.

Eligibility

Is LDN Right For You?

It may be considered for adults whose diagnosis, symptoms and current medications are reviewed by a licensed provider. Not appropriate for everyone — it is not appropriate for anyone taking opioid medication.

Medical oversight

The Physicians Behind Every Prescription

Our patients are supported by a nationwide team of licensed physicians and nurse practitioners through the Arora Health provider network. Every order is reviewed by a licensed provider and prescribed according to medical best practices and the laws of your state.

Sean Arora, MD — CEO & Co-Founder

Board-certified physician and entrepreneur who leads nationwide medical oversight and the provider network, focused on expanding access to high-quality wellness and longevity care.

Shannon Arora, MD — Chief Medical Officer

Board-certified physician overseeing clinical quality, protocol development and provider education across the network, with a background in hospital medicine and preventive wellness.

Alex Saucedo, MD — Lead Medical Director

Dual board-certified physician with more than eight years of clinical and leadership experience, specializing in clinical oversight, patient safety and regulatory compliance.

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Frequently Asked Questions

Answers to the most common questions about how Low Dose Naltrexone works, who it may be right for, and what to expect during treatment.

It is prescribed off-label for a range of chronic pain, fatigue and inflammatory conditions. Off-label means it is being used outside its approved indication, which is a decision your provider makes with you.

Standard naltrexone is 50 mg and approved for alcohol and opioid dependence. LDN is roughly 1 to 4.5 mg, prescribed for entirely different proposed effects.

Most providers start at the lowest strength and titrate upward as tolerated. Strength is provider-determined at every stage.

Most protocols are nightly. Your provider will confirm the timing for your prescription.

No. Naltrexone blocks opioid receptors, so it is not appropriate alongside opioid medication. Tell your provider about every medication you take.

Vivid dreams and sleep disturbance in the first weeks are the most commonly reported, and often settle. Report anything persistent to your provider.

No. Compounded medications are not FDA-approved and are not evaluated by the FDA for safety or efficacy.

Individual results vary and LDN is generally assessed over months rather than days. Your provider will set expectations.

Find Out If Low Dose Naltrexone Is Right for You

Complete a secure online intake and a U.S.-licensed provider will review your health history, symptoms and goals to determine whether this therapy — or a different one — fits your needs.